All about diseases


Thursday, June 21, 2012

Diabetes Mellitus


Diabetes comes from Greek, and it means a siphon. Aretus the Cappadocian, a Greek physician during the second century A.D., named the condition diabainein. He described patients who were passing too much water (polyuria) - like a siphon. The word became "diabetes" from the English adoption of the Medieval Latin diabetes.

In 1675 Thomas Willis added mellitus to the term, although it is commonly referred to simply as diabetes. Mel in Latin means honey; the urine and blood of people with diabetes has excess glucose, and glucose is sweet like honey. Diabetes mellitus could literally mean "siphoning off sweet water".

In ancient China people observed that ants would be attracted to some people's urine, because it was sweet. The term "Sweet Urine Disease" was coined

Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, or its action, or both. Diabetes mellitus, commonly referred to as diabetes (as it will be in this article) was first identified as a disease associated with "sweet urine," and excessive muscle loss in the ancient world. Elevated levels of blood glucose (hyperglycemia) lead to spillage of glucose into the urine, hence the term sweet urine.

Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level. When the blood glucose elevates (for example, after eating food), insulin is released from the pancreas to normalize the glucose level. In patients with diabetes, the absence or insufficient production of insulin causes hyperglycemia. Diabetes is a chronic medical condition, meaning that although it can be controlled, it lasts a lifetime.
         
Type 1 Diabetes

Type 1 diabetes is an autoimmune disease. An autoimmune disease results when the body's system for fighting infection (the immune system) turns against a part of the body. In diabetes, the immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. A person who has type 1 diabetes must take insulin daily to live..

Symptoms of type 1 diabetes usually develop over a short period, although beta cell destruction can begin years earlier. Symptoms include increased thirst and urination, constant hunger, weight loss, blurred vision, and extreme fatigue. If not diagnosed and treated with insulin, a person with type 1 diabetes can lapse into a life-threatening diabetic coma, also known as diabetic ketoacidosis.

Type 2 Diabetes

The most common form of diabetes is type 2 diabetes. About 90 to 95 percent of people with diabetes have type 2. This form of diabetes is associated with older age, obesity, family history of diabetes, previous history of gestational diabetes, physical inactivity, and ethnicity. About 80 percent of people with type 2 diabetes are overweight
.
The symptoms of type 2 diabetes develop gradually. Their onset is not as sudden as in type 1 diabetes. Symptoms may include fatigue or nausea, frequent urination, unusual thirst, weight loss, blurred vision, frequent infections, and slow healing of wounds or sores. Some people have no symptoms.

Gestational Diabetes

Gestational diabetes develops only during pregnancy. Like type 2 diabetes, it occurs more often in African Americans, American Indians, Hispanic Americans, and among women with a family history of diabetes. Women who have had gestational diabetes have a 20 to 50 percent chance of developing type 2 diabetes within 5 to 10 years

Recommended target blood glucose level ranges

The International Diabetes Federation have specified the following blood glucose levels:
IDF recommended target blood glucose level ranges
Target Levels
by Type
Before meals
(pre prandial)
2 hours after
(post prandial)
Non-diabetic
4.0 to 5.9 mmol/L
under 7.8 mmol/L*
Type 2 diabetes
4 to 7 mmol/L
under 8.5 mmol/L
Type 1 diabetes
4 to 7 mmol/L
under 9 mmol/L
Children w/ diabetes
4 to 8 mmol/L
under 10 mmol/L

Normal blood sugar ranges

For the majority of healthy individuals, normal blood sugar levels are as follows:
  • The normal blood glucose level in humans is about 4 mM (4 mmol/L or 72 mg/dL)
  • The body, when operating normally, restores the blood sugar level to a range of about 4.4 to 6.1 mmol/L (82 to 110 mg/dL)
  • Shortly after eating the blood glucose level may rise temporarily up to 7.8 mmol/L (140 mg/dL)

Diabetes comes from Greek, and it means a siphon. Aretus the Cappadocian, a Greek physician during the second century A.D., named the condition diabainein. He described patients who were passing too much water (polyuria) - like a siphon. The word became "diabetes" from the English adoption of the Medieval Latin diabetes.
In 1675 Thomas Willis added mellitus to the term, although it is commonly referred to simply as diabetes. Mel in Latin means honey; the urine and blood of people with diabetes has excess glucose, and glucose is sweet like honey. Diabetes mellitus could literally mean "siphoning off sweet water".
In ancient China people observed that ants would be attracted to some people's urine, because it was sweet. The term "Sweet Urine Disease" was coined.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, or its action, or both. Diabetes mellitus, commonly referred to as diabetes (as it will be in this article) was first identified as a disease associated with "sweet urine," and excessive muscle loss in the ancient world. Elevated levels of blood glucose (hyperglycemia) lead to spillage of glucose into the urine, hence the term sweet urine.
Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level. When the blood glucose elevates (for example, after eating food), insulin is released from the pancreas to normalize the glucose level. In patients with diabetes, the absence or insufficient production of insulin causes hyperglycemia. Diabetes is a chronic medical condition, meaning that although it can be controlled, it lasts a lifetime. `         
Type 1 Diabetes

Type 1 diabetes is an autoimmune disease. An autoimmune disease results when the body's system for fighting infection (the immune system) turns against a part of the body. In diabetes, the immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. A person who has type 1 diabetes must take insulin daily to live..

Symptoms of type 1 diabetes usually develop over a short period, although beta cell destruction can begin years earlier. Symptoms include increased thirst and urination, constant hunger, weight loss, blurred vision, and extreme fatigue. If not diagnosed and treated with insulin, a person with type 1 diabetes can lapse into a life-threatening diabetic coma, also known as diabetic ketoacidosis.

Type 2 Diabetes

The most common form of diabetes is type 2 diabetes. About 90 to 95 percent of people with diabetes have type 2. This form of diabetes is associated with older age, obesity, family history of diabetes, previous history of gestational diabetes, physical inactivity, and ethnicity. About 80 percent of people with type 2 diabetes are overweight.
The symptoms of type 2 diabetes develop gradually. Their onset is not as sudden as in type 1 diabetes. Symptoms may include fatigue or nausea, frequent urination, unusual thirst, weight loss, blurred vision, frequent infections, and slow healing of wounds or sores. Some people have no symptoms.

Gestational Diabetes

Gestational diabetes develops only during pregnancy. Like type 2 diabetes, it occurs more often in African Americans, American Indians, Hispanic Americans, and among women with a family history of diabetes. Women who have had gestational diabetes have a 20 to 50 percent chance of developing type 2 diabetes within 5 to 10 years

Recommended target blood glucose level ranges

The International Diabetes Federation have specified the following blood glucose levels:
IDF recommended target blood glucose level ranges
Target Levels
by Type
Before meals
(pre prandial)
2 hours after
(post prandial)
Non-diabetic
4.0 to 5.9 mmol/L
under 7.8 mmol/L*
Type 2 diabetes
4 to 7 mmol/L
under 8.5 mmol/L
Type 1 diabetes
4 to 7 mmol/L
under 9 mmol/L
Children w/ diabetes
4 to 8 mmol/L
under 10 mmol/L
Normal blood sugar ranges
For the majority of healthy individuals, normal blood sugar levels are as follows:
  • The normal blood glucose level in humans is about 4 mM (4 mmol/L or 72 mg/dL)
  • The body, when operating normally, restores the blood sugar level to a range of about 4.4 to 6.1 mmol/L (82 to 110 mg/dL)
  • Shortly after eating the blood glucose level may rise temporarily up to 7.8 mmol/L (140 mg/dL)

Diabetes treatment

Diabetes medicines

insulin

If your body no longer makes enough insulin, you'll need to take it. Insulin is used for all types of diabetes. Your doctor can help you decide which way of taking insulin is best for you.

·         Taking injections. You'll give yourself shots using a needle and syringe. The syringe is a hollow tube with a plunger. You will put your dose of insulin into the tube. Some people use an insulin pen, which looks like a pen but has a needle for its point.

·         Using an insulin pump. An insulin pump is a small machine about the size of a cell phone, worn outside of your body on a belt or in a pocket or pouch. The pump connects to a small plastic tube and a very small needle. The needle is inserted under the skin and stays in for several days. Insulin is pumped from the machine through the tube into your body.

           Using an insulin jet injector. The jet injector, which looks like a large pen, sends a fine spray                     of  insulin through the skin with high-pressure air instead of a needle.

Diabetes Pills

Along with meal planning and physical activity, diabetes pills help people with type 2 diabetes or gestational diabetes keep their blood glucose levels on target. Several kinds of pills are available. Each works in a different way. Many people take two or three kinds of pills. Some people take combination pills. Combination pills contain two kinds of diabetes medicine in one tablet. Some people take pills and insulin.
Your doctor may ask you to try one kind of pill. If it doesn't help you reach your blood glucose targets, your doctor may ask you to
  • take more of the same pill
  • add another kind of pill
  • change to another type of pill
  • start taking insulin
  • start taking another injected medicine
If your doctor suggests that you take insulin or another injected medicine, it doesn't mean your diabetes is getting worse. Instead, it means you need insulin or another type of medicine to reach your blood glucose targets.

There are some useful herbs you  can take for treatment of diabetes such as:
  • Bitter Gourd (Momordica charantia)
  • Bael (Aegle marmelos)
  • Gurmar Leaves (Gymnema sylvestrae)
  • Fenugreek (Trigonella foenum graecum)
  • Turmeric (Curcuma longa)
  • Onion (Allium cepa)
  • Nayantatra (Vinca rosa)
  • Neem (Azadirachtha indica)
  • Garlic (Allium sativum)
  • Sagar gota (Ceasalpinia crista)
 Diabetes treatment with stem cells

The other treatment for diabetes is a fetal stem cell transplantation-based method (excluding pancreatic beta-cells) for diabetes treatment. This method has proven to be effective for diabetes types I and II treatment and is protected by patents of many countries. Stem cell treatment of diabetes results in pronounced hypoglycemic effect, i.e. decrease of blood sugar level, allowing to reduce the dose of exogenous insulin by 50–70%.  Diabetes treatment with fetal stem cells induces long-term clinical remission in more than half of cases.

Effects of diabetes treatment with fetal stem cells

Stem cell treatment of diabetes leads to significant improvement in patient’s condition. In some cases at the early stages of the disease, it may result even in the full recovery. After the stem cell therapy, diabetes mellitus patients report normalization of immunological and hematological indices, reduced manifestations of micro- and macroangiopathy and trophic disturbances, restoration of workability. In case of treatment the disease progression is hindered, and periods of remission become 2–3 times longer. Severity and frequency of diabetes complications decrease. Life quality and average life expectancy increase.

There are some useful herbs you  can take for treatment of diabetes such as:

  • Bitter Gourd (Momordica charantia)
  • Bael (Aegle marmelos)
  • Gurmar Leaves (Gymnema sylvestrae)
  • Fenugreek (Trigonella foenum graecum)
  • Turmeric (Curcuma longa)
  • Onion (Allium cepa)
  • Nayantatra (Vinca rosa)
  • Neem (Azadirachtha indica)
  • Garlic (Allium sativum)
  • Sagar gota (Ceasalpinia crista)
 Diabetes treatment with stem cells

 The other treatment for diabetes is a fetal stem cell transplantation-based method (excluding pancreatic beta-cells) for diabetes treatment. This method has proven to be effective for diabetes types I and II treatment and is protected by patents of many countries. Stem cell treatment of diabetes results in pronounced hypoglycemic effect, i.e. decrease of blood sugar level, allowing to reduce the dose of exogenous insulin by 50–70%.  Diabetes treatment with fetal stem cells induces long-term clinical remission in more than half of cases.

Effects of diabetes treatment with fetal stem cells

Stem cell treatment of diabetes leads to significant improvement in patient’s condition. In some cases at the early stages of the disease, it may result even in the full recovery. After the stem cell therapy, diabetes mellitus patients report normalization of immunological and hematological indices, reduced manifestations of micro- and macroangiopathy and trophic disturbances, restoration of workability. In case of treatment the disease progression is hindered, and periods of remission become 2–3 times longer. Severity and frequency of diabetes complications decrease. Life quality and average life expectancy increase.

Diabetes prevention: 5 tips for taking control

Tip 1: Get more physical activity

There are many benefits to regular physical activity. Exercise can help you:
  • Lose weight
  • Lower your blood sugar
  • Boosts your sensitivity to insulin — which helps keep your blood sugar within a normal range
Tip 2: Get plenty of fiber

It's rough, it's tough — and it may help you:
  • Reduce your risk of diabetes by improving your blood sugar control
  • Lower your risk of heart disease
  • Promote weight loss by helping you feel full
Tip 3: Go for whole grains

Although it's not clear why, whole grains may reduce your risk of diabetes and help maintain blood sugar levels. Try to make at least half your grains whole grains

Tip 4: Lose extra weight

If you're overweight, diabetes prevention may hinge on weight loss. Every pound you lose can improve your health. And you may be surprised by how much. In one study, overweight adults reduced their diabetes risk by 16 percent for every kilogram (2.2 pounds) of weight lost.

Tip 5: Skip fad diets and make healthier choices

Low-carb diets, the glycemic index diet or other fad diets may help you lose weight at first, but their effectiveness at preventing diabetes isn't known nor are their long-term effects. And by excluding or strictly limiting a particular food group, you may be giving up essential nutrients.